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非瓣膜性房颤患者增龄性血栓栓塞危险和抗凝出血风险研究(1)
http://www.100md.com 2015年10月1日 中国医学人文杂志 2015年第10期
     【摘 要】研究非瓣膜性房颤患者血栓栓塞危险和抗栓治疗出血风险与年龄的相关性。方法:以合并缺血性脑卒中患者为研究对象,以评分量表研究不同年龄段非瓣膜性房颤患者的血栓栓塞危险和抗凝出血风险。按照患者是否大于65岁分为研究组和对照组,对研究对象进行CHA2DS2-VASc评分和HAS-BLED评分并且进行对比分析。结果:CHA2DS2-VASc评分和HAS-BLED评分结果都随年龄增加而增加,老年组患者各项积分明显高于对照组。结论:非瓣膜性房颤患者血栓栓塞危险和抗凝出血风险与年龄增加存在相关性,老年患者的抗栓管理更加需要综合衡量。

    【关键词】非瓣膜性房颤;栓塞;出血

    Objective This study aimed to evaluate the relationship between thromboembolism risk and bleeding risk in patients with non-valvular atrial fibrillation of different age.All the patients were divided into research group(≥65 years)and the control group(<65 years).The CHA2DS2-VASc score and the HAS-BLED score were analyzed.Result The CHA2DS2-VASc score and the HASBLED score were both significantly increased with aging.Conclusion The bleeding risk increased similarly as the thromboembotic risk with increasing age in patients with non-valvular atrial fibrillation.Antithrombotic treatment of elderly patients need a comprehensive measure.

    Key word:non-valvular atrial fibrillation;thromboembolism;bleeding

    非瓣膜性房颤(non-valvular atrial fibrillation ......
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