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转移因子口服液治疗艾滋病合并肺结核疗效观察
http://www.100md.com 2008年12月1日 《医学发展》 2008年第12期
转移因子口服液治疗艾滋病合并肺结核疗效观察

     摘 要目的:观察转移因子治疗艾滋病合并肺结核的临床疗效。方法:将100例艾滋病合并肺结核患者随机分为治疗组与对照组,对照组给予正规抗结核治疗,治疗组加服转移因子口服液;观察两组治疗前后白细胞(WBC)指标、CD4+值水平的变化以及临床症状好转情况。结果:治疗组总有效率94%,对照组总有效率72%,两组总有效率对比差异有统计学意义(x2=8.57, P<0.05)。治疗组平均CD4+T淋巴细胞上升189个/μl,对照组平均CD4+T淋巴细胞上升71个/μl,治疗组与对照组比较差异有统计学意义(t =11.6, P<0.05)。治疗组治疗前后白细胞值比较差异有统计学意义(t =57.91, P<0.05)。对照组治疗前后白细胞值比较差异无统计学意义(t =1.06, P>0.05)。结论:转移因子治疗艾滋病合并肺结核有明显疗效。

    关键词转移因子;AIDS;肺结核;疗效

    AbstractObjective:To observe the clinical efficacy of transfer factor oral solution in treatment of AIDS complicated with pulmonary tuberculosis. Methods:100 patients with AIDS complicated by pulmonary tuberculosis were divided into treatment group and control group randomly. The control group was given the treatment with regular anti-tuberculosis drug and the treatment group was given transfer factor oral solution in addition. We observe the allaxis in the numbers of leukocyte and CD4+Cell and the change in symptom before and after treatment. Results: The total effective percentage of treatment group was 94%. The total effective percentage of control group was 72%. There was statistical significance between the effective percentages of two groups (x2=8.57, p<0.05). There was statistical significance in the different growth of CD4+ cell between two groups (t=11.6, p<0.05). There was statistical significance between the numbers of leukocyte before and after treatment (t=57.91, p<0.05). There wasn’t statistical significance between the numbers of CD4+ cells before and after treatment (t=1.06, p>0.05). Conclusions:The curative effect of transfer factor oral solution in treatment of AIDS complicated by pulmonary tuberculosis is remarkable. ......

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