64排螺旋CT低剂量扫描并靶扫诊断高危人群早期肺癌的临床观察(1)
[摘要]目的 比较分析低剂量64排螺旋CT扫描并靶扫与传统DR胸片筛选早期肺癌的优缺点，评价低剂量64排螺旋CT扫描并靶扫描在早期肺癌筛选中的应用价值。方法 选取2015年1月～2016年3月在我院体检科进行体检的人群，共筛选出肺癌高危人群362人，对所有高危人群行传统胸片检查和64排螺旋CT低剂量扫描并靶扫检查，由两名医生对结果进行双盲观察诊断，记录两种检查方式的检查结果，并对其进行对比分析。结果 传统DR胸片检出高危人群25例有肺部结节，检出率为6.91%，CT检出58例有肺部结节，检出率为16.02%，CT检出率明显高于传统DR胸片，差异有统计学意义(P<0.05)；传统DR胸片最终检出肺癌2人，检出率为0.55%，CT并靶扫最终检出肺癌9人，检出率为2.49%，CT并靶扫检出率明显高于传统DR胸片，差异有统计学意义(P<0.05)。结论 64排螺旋CT低剂量扫描并靶扫的早期肺癌检出率明显高于传统DR胸片，因此临床工作者在对早期肺癌筛查中应重视64排螺旋CT低剂量扫描并靶扫，而不应单单关注传统DR胸片的检查结果。
[关键词]CT；靶扫；早期肺癌；诊断
[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721(2017)08(c)-0045-03
[Abstract]Objective To compare the advantages and disadvantages of low-dose 64-slice spiral CT and target scanning，and traditional DR chest radiography on screening early lung cancer population，and evaluate the application value of low-dose 64-slice spiral CT scanning with target scanning.Methods From January 2015 to March 2016，362 people with high risk of lung cancer were screened after physical examinations in our physical examination department were selected.All participants were provided with traditional chest radiography and low-dose 64-slice spiral CT scanning with target scanning.Two physicians were invited for outcome observation and diagnosis in double-blind.The results by the two inspection methods were recorded and comparatively analyzed.Results In traditional DR chest radiography.25 people in high risk of lung cancer group were detected with pulmonary nodules，and the detection rate was 6.91%.In CT，58 participants were detected accounting for 16.02%.The detection rate in CT group was much higher than that in the traditional DR chest radiography (P<0.05).In traditional DR chest radiography，2 people were finally diagnosed as lung cancer，and the detection rate was 0.55%，while in CT scanning with target scanning，9 ones were detected with lung cancer accounting for 2.49%.The detection rate in the latter was higher (P<0.05).Conclusion The detection rate of early lung cancer by 64-slice spiral CT in a low-dose scanning and target scanning is remarkably higher than that by traditional DR chest radiography.Therefore，clinical physicians should attach great importance to 64-slice spiral CT in a low-dose scanning and target scanning，not only focus on the examination results by traditional DR chest radiography.
[Key words]CT；Target scanning；Early lung cancer；Diagnosis
近年來，随着人们的生活方式的改变，生活水平的提高及老龄化的到来，我国癌症种类发生比出现了变化，肿瘤死亡率出现了下降的趋势，但肺癌死亡率却呈上升态势[1-2]。目前国内对早期肺癌的筛选多采用常规DR胸片，若发现有非钙化结节时，则使用CT进行筛查。但常规X线胸片极有可能出现漏诊的现象，使肺癌发展至晚期才被发现，很大程度上影响了患者的早期治疗，导致肺癌患者的5年生存率明显降低[3-4]。CT扫描虽然可以精准地检测出早期肺部结节，由于有较大的辐射量，临床医生使用较少，因此目前临床上很难推广。随着CT低剂量扫描的发展，已很好地解决了辐射量大、漏诊的现象[5-6]。本研究将对比64排螺旋CT低剂量扫描并靶扫与DR胸片诊断高危人群早期肺癌，记录并分析结果，为患者的早期诊断提供理论依据。, 百拇医药(李韡)
[关键词]CT；靶扫；早期肺癌；诊断
[中图分类号] R734.2 [文献标识码] A [文章编号] 1674-4721(2017)08(c)-0045-03
[Abstract]Objective To compare the advantages and disadvantages of low-dose 64-slice spiral CT and target scanning，and traditional DR chest radiography on screening early lung cancer population，and evaluate the application value of low-dose 64-slice spiral CT scanning with target scanning.Methods From January 2015 to March 2016，362 people with high risk of lung cancer were screened after physical examinations in our physical examination department were selected.All participants were provided with traditional chest radiography and low-dose 64-slice spiral CT scanning with target scanning.Two physicians were invited for outcome observation and diagnosis in double-blind.The results by the two inspection methods were recorded and comparatively analyzed.Results In traditional DR chest radiography.25 people in high risk of lung cancer group were detected with pulmonary nodules，and the detection rate was 6.91%.In CT，58 participants were detected accounting for 16.02%.The detection rate in CT group was much higher than that in the traditional DR chest radiography (P<0.05).In traditional DR chest radiography，2 people were finally diagnosed as lung cancer，and the detection rate was 0.55%，while in CT scanning with target scanning，9 ones were detected with lung cancer accounting for 2.49%.The detection rate in the latter was higher (P<0.05).Conclusion The detection rate of early lung cancer by 64-slice spiral CT in a low-dose scanning and target scanning is remarkably higher than that by traditional DR chest radiography.Therefore，clinical physicians should attach great importance to 64-slice spiral CT in a low-dose scanning and target scanning，not only focus on the examination results by traditional DR chest radiography.
[Key words]CT；Target scanning；Early lung cancer；Diagnosis
近年來，随着人们的生活方式的改变，生活水平的提高及老龄化的到来，我国癌症种类发生比出现了变化，肿瘤死亡率出现了下降的趋势，但肺癌死亡率却呈上升态势[1-2]。目前国内对早期肺癌的筛选多采用常规DR胸片，若发现有非钙化结节时，则使用CT进行筛查。但常规X线胸片极有可能出现漏诊的现象，使肺癌发展至晚期才被发现，很大程度上影响了患者的早期治疗，导致肺癌患者的5年生存率明显降低[3-4]。CT扫描虽然可以精准地检测出早期肺部结节，由于有较大的辐射量，临床医生使用较少，因此目前临床上很难推广。随着CT低剂量扫描的发展，已很好地解决了辐射量大、漏诊的现象[5-6]。本研究将对比64排螺旋CT低剂量扫描并靶扫与DR胸片诊断高危人群早期肺癌，记录并分析结果，为患者的早期诊断提供理论依据。, 百拇医药(李韡)