半夏泻心汤治疗结直肠癌术后肝脾不和证的临床研究(1)

http://www.100md.com 2017年4月1日 《世界中医药》 20177

     摘要 目的：觀察半夏泻心汤治疗结直肠癌术后肝脾不和证的临床疗效。方法：选取郑州市中医院2014年9月至2016年6月期间收治的140例结直肠癌术后肝脾不和证患者为研究对象，按照随机数表法分为对照组( n =70)和观察组( n =70)。对照组采用常规内科治疗，观察组在对照组基础上采用半夏泻心汤治疗。比较2组治疗前后临床症状、生命质量、血清癌胚抗原(Carcino Embryonic Antigen，CEA)水平，并评价2组临床疗效及安全性。结果：观察组临床疗效总有率为90.00%(63/70)，明显高于对照组71.43%(50/70)，差异有统计学意义( P <0.05)；与治疗前比较，观察组与对照组中医症候积分、血清CEA水平在治疗后均明显下降，而卡氏(Karnofsky，KPS)评分上升，且观察组上述观察指标均优于对照组，差异有统计学意义( P <0.05)；治疗期间2组均未出现肝肾功能异常及不良反应。结论：对结直肠癌术后肝脾不和证患者采用半夏泻心汤治疗，可显著提高临床疗效，缓解临床症状，降低血清CEA水平，促进患者身体恢复，提高患者生命质量，具有临床推广意义。
, http://www.100md.com
    关键词 半夏泻心汤；结直肠癌术；肝脾不和证；临床疗效；CEA水平；生命质量

    Clinical Study on Banxia Xiexin Decoction in Treatment of Disharmony between Liver and Spleen after Colorectal Cancer Surgery

    Li Yingjie， Qiu Shuguang， Liang Jun

    (Zhengzhou Hospital of Traditional Chinese Medicine， Zhengzhou 450007， China)

    Abstract Objective： To observe the clinical efficacy of Banxia Xiexin Decoction in treatment of disharmony between liver and spleen after colorectal cancer surgery. Methods： A total of 140 patients with disharmony between liver and spleen after colorectal cancer surgery admitted into the hospital from September 2014 to June 2016 were selected as research subjects and were divided into control group ( n =70) and research group ( n =70) by random number table. Patients in the control group took conventional medical treatment， while patients in the research group additionally took Banxia Xiexin decoction on the basis of treatment for the control group. The clinical symptoms， survival quality and carcino embryonic antigen (CEA) level of the two groups before and after the treatment were compared. The clinical efficacy and safety of the two groups were evaluated. Results： The total effective rate of the research group was 90.00% (63/70)， which was significantly higher than 71.43% (50/70) of the control group ( P <0.05). The TCM symptom score， serum CEA level of two groups significantly decreased after treatment compared with before treatment， but Karnofsky (KPS) score increased. The above indexes of the research group were all better than those of the control group ( P <0.05). There was no liver and kidney dysfunction and adverse reactions in both the two groups during the treatment. Conclusion： Banxia Xiexin decoction for disharmony between liver and spleen after colorectal cancer surgery can significantly increase clinical efficacy， relieve clinical symptoms， decrease serum CEA level， promote patients′ recovery and improve survival quality， which has significance of clinical promotion., 百拇医药(李应杰 邱曙光 梁君)

第 1 2 3 4 页 下一页

    百拇医药网 http://www.100md.com/html/paper/1673-7202/2017/07/09.htm