老年性痴呆动物模型的研究进展(5)
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[18]Santacruz K,Lewis J,Spires T,et al.Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function[J].Science,2005,309(5733):476-481.
[19]Lewis J,Dickson DW,Lin WL,et al.Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP[J].Science(S0036-8075), 2001,293(5534):1487-1491.
[20]Oddo S,Caccamo A,Jason D,et al.Triple -transgenic Model of Alzheimer's Disease with Plaqueand Tangles:Intracellular Aβand Synaptic Dysfunction[J].Neuron,2003,39: 409-421.
[21]Duff K,Eckman C,Zehr C,et al.Increase Amyloid-beta42(43) in Brains of Mice Expressing Mutant Presenilin 1[J].Nature,1996,38(6602):710-713.
[22]Hirsch-Reinshagen,V.Maia LF,Burgess BL,et al.The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease[J].Biol. Chem,2005,280(52):43243-43256.
[23]Capsoni-S，Ugolini-G，Comparini-A，et al.Alzheimer-Like Neurodegeneration in Aged Antinerve Growth-Factor Transgenic Mice[J].proceedings of the national academy of sciences of the united states of america，2000, 97(12):6826-6831.
[24]Dixit R,Ross J. L，Goldman,Y. E. et al.Differential regulation of dynein and kinesin motor proteins by tau[J].Science,2008,319(5866):1086-1089.
(收稿日期：2008-10-07 修回日期：2008-11-28)
(编辑：梁明佩), 百拇医药(凌雁武 黄瑞雅)
[18]Santacruz K,Lewis J,Spires T,et al.Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function[J].Science,2005,309(5733):476-481.
[19]Lewis J,Dickson DW,Lin WL,et al.Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP[J].Science(S0036-8075), 2001,293(5534):1487-1491.
[20]Oddo S,Caccamo A,Jason D,et al.Triple -transgenic Model of Alzheimer's Disease with Plaqueand Tangles:Intracellular Aβand Synaptic Dysfunction[J].Neuron,2003,39: 409-421.
[21]Duff K,Eckman C,Zehr C,et al.Increase Amyloid-beta42(43) in Brains of Mice Expressing Mutant Presenilin 1[J].Nature,1996,38(6602):710-713.
[22]Hirsch-Reinshagen,V.Maia LF,Burgess BL,et al.The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease[J].Biol. Chem,2005,280(52):43243-43256.
[23]Capsoni-S，Ugolini-G，Comparini-A，et al.Alzheimer-Like Neurodegeneration in Aged Antinerve Growth-Factor Transgenic Mice[J].proceedings of the national academy of sciences of the united states of america，2000, 97(12):6826-6831.
[24]Dixit R,Ross J. L，Goldman,Y. E. et al.Differential regulation of dynein and kinesin motor proteins by tau[J].Science,2008,319(5866):1086-1089.
(收稿日期：2008-10-07 修回日期：2008-11-28)
(编辑：梁明佩), 百拇医药(凌雁武 黄瑞雅)