硒酵母抗癌活性研究
硒酵母;,亚硒酸钠;,抗癌;,宫颈癌;,肝癌,,硒酵母;,亚硒酸钠;,抗癌;,宫颈癌;,肝癌,1器材,2方法与结果,3讨论,参考文献:
摘要:目的研究不同浓度硒酵母对肿瘤细胞的抑制作用。方法体外培养宫颈癌细胞,经不同浓度的硒酵母处理,MTT法测定硒酵母对肿瘤细胞的抑制作用。小鼠体内接种腹水型肝癌细胞 H22,观察硒酵母体内抗肿瘤作用。测量小鼠体重变化,CD4+,CD8+含量,白蛋白、总蛋白含量。结果含硒5 μg/ml的硒酵母即能显著抑制荷癌小鼠腹水生成,提高 CD4+,CD8+比值,升高血清白蛋白及总蛋白含量(P<0.01)。结论硒酵母具有良好的抗肿瘤作用,其作用优于同剂量的亚硒酸钠。关键词:硒酵母; 亚硒酸钠; 抗癌; 宫颈癌; 肝癌
Anticancer Activity of Selenium Yeast
WANG Junzhi, ZOU Kun, XIAO Lingling, YAO Juan
(Three Gorges University, Hubei Provincial Key Laboratory for Natural Product Research and Utilization, Yichang 443002,China;Hubei Angel Yeast Co. Ltd, Yichang 443003,China)
Abstract:ObjectiveTo study the anticancer activity of different density selenium yeast.MethodsCultured cancer cells of cervix in vitro,treated by different density selenium yeast,used the way of MTT to determine the activity of inhibition against the tumour cell.. Inoculated hepatoma cell H22 to mouse abdominal cavity ,observed the anticancer activity of selenium yeast in vivo.Measured the changes of body weight ,content of CD4+ ......
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