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海洛因依赖患者心率变异性分析
http://www.100md.com 《中华现代临床医学杂志》 2000年第20期
海洛因依赖者;动态心电图;心率变异性,,],海洛因依赖者;动态心电图;心率变异性,1资料与方法,2结果,3讨论,[参考文献]
     [摘要] 目的 观察海洛因依赖患者心率变异性各项指标的临床意义。 方法 对86例海洛因依赖患者与89例对照组进行全程24 h动态心电图检查,并行心率变异性时域和频域分析对比。 结果 海洛因依赖患者组SDNN、SDANN、SDNNI、rMSSD、PNN50降低,LF、HF也降低,LF/HF增大,差异有显著性(P<0.05),HRV直方图有特征性变化。 结论 HRV能较直观反映海洛因依赖患者的交感神经及迷走神经的功能失衡,且稳定性、重复性及敏感性较好。因此,HRV分析是一种为临床早期发现海洛因依赖患者心脏自主神经功能异常的较好方法。

    [关键词] 海洛因依赖者;动态心电图;心率变异性

    Analysis of heart rate variability to the drug addicts

    ZHANG Guoqiang,ZHAO Jianping.

    Department of Zhejiang Provincial Corps Hospital,Zhejiang 314000,China

    [Abstract] Objective To observe clinical significance of heart rate variability of the drug addicts. Methods Make a 24-hour dynamic ECG to 86 drug addicts and 89 normal subjects.Then make a conbrast analysis to the time domain and frequency domain of heart rate variability. Results SDNN,SDANN,SDNNIdex,RMSSD,PNN50,LF and HFHRV are significanbly lower as well as LF and HF and LF/HF is significanbly higher in palienbs than those in normal subjects (P<0.05).HRV has a characterisibic change. Conclusion HRV can easily reveal that whether the sympathetic nerve and vagus nerve of the drug addicts have lost the functional balance.HRV has a good stability and sensibivity and can be used repeabedly.So HRV analysis is a good way for the clinic diagnose to find whether the aubonomous nerve system of the drug addicts is functionally abnormal. ......

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