【摘 要】 目的 探讨可溶性细胞间黏附分子-1(sICAM-1)水平与白癜风活动程度的关系和意义。 方法 sICAM-1检测采用酶联免疫吸附试验(ELISA)方法。 结果 (1)白癜风患者血清sICAM-1平均水平为769.80ng/ml，显著高于正常对照组642.40ng/ml(P<0.001)。(2)进展期白癜风患者血清sICAM-1平均水平为802.32ng/ml，显著高于稳定期654.15ng/ml(P<0.001)。(3)泛发型白癜风患者血清SICM-1平均水平为801.40ng/ml，显著高于局限型675.45ng/ml(P<0.001)。(4)稳定期和局限型白癜风患者血清sICAM-1水平与正常对照组差异无显著性(P均>0.05)。 结论 sICAM-1可能参与白癜风的发病，与白癜风活动性和严重程度相关。

    【关键词】 白癜风;酶联免疫吸附试验;可溶性细胞间黏附分子-1

    Clinic significance of sICAM┐1in patients with vitiligo

    DU Jiang，HONG Wei-song.

    (Chaohu College of Vocational Technolo-gy，Anhui238000，China)

    【Abstract】 Objective To investigate the relationship between degree of sICAM-1and degree of vitiligo activity，and discuss its significance.Methods sICAM-1was detected by enzymelinked immunoabsorbent assay.Results ①The average concentration of sICAM-1in the sera of patients with vitiligo is769.80ng/ml ......