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决明子降血脂有效部位的研究
http://www.100md.com 《时珍国医国药》 2006年第6期
决明子;,血脂;,有效部位,,决明子;,血脂;,有效部位,摘要,关键词,1材料,2方法,3实验结果,4讨论,参考文献
     摘要:目的研究决明子降血脂的有效部位。方法采用系统溶剂提取法对决明子进行分部位提取,制得决明子提取物。建立小鼠高脂血症模型,对各提取物进行降血脂药效学研究,确定决明子降血脂有效部位。结果决明子正丁醇提取物具有明显的降血脂作用,能显著降低高脂血症小鼠血清总胆固醇(TC)和甘油三酯(TG)。结论 正丁醇提取物为决明子降血脂有效部位。

    关键词:决明子; 血脂; 有效部位

    Study on the Effective Part of Reducing Blood Lipid in Semen Cassiae

    ZHANG Jiaxiong, WAN Li, HU Yijuan, QU Qiaoling, SHI Janyou

    (College of Pharmacy, Chengdu University of TCM, Chengdu 611730, China)

    Abstract:ObjectiveTo study the effective part of reducing blood lipid in Semen Cassiae.MethodsThe extracts of Semen Cassia were processed by dissolvent subsection-extracting, and then adopt hyperlipidemia model by mice to study the pharmacological effect of the different extracts from Semen Cassiae. ResultsThe n-BuOH extracts have obvious action of reducing blood lipid. It can notably lower total cholesterin (TC)and glycerinum( TG ) in serum from mice of hyperlipidemia.ConclusionnBuOH extracts is the active part of reducing blood lipid in Semen Cassiae.

    Key words: Semen Cassiae; Blood Lipid; Effective Part

    决明子为《中国药典》2005年版收载品种 ......

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