肌钙蛋白;_____肌钙蛋白;心肌梗死;急性冠状动脉综合征

肌钙蛋白I定量检测在急性非Q波心肌梗死的诊断价值

http://www.100md.com 《广东药学院学报》 2003年第2期

肌钙蛋白;,,肌钙蛋白;心肌梗死;急性冠状动脉综合征,1资料和方法,2结果,3讨论

     摘要目的：观察肌钙蛋白I(cTnI)在急性非Q波心肌梗死(NQMI)的诊断价值。方法：用微粒子免疫化学发光法定量检测23例NQMI患者血清cTnI浓度，将其阳性率与血清肌酸激酶同工酶(CKMB)作比较。结果：cTnI升高共23例，阳性率100%，峰值平均值为诊断急性心肌梗死界定值的20倍。CKMB升高16例，阳性率为69.6%，峰值平均值为正常值上限的5.6倍。结论：肌钙蛋白I在NQMI的诊断敏感性显著高于CKMB。

    关键词肌钙蛋白;心肌梗死;急性冠状动脉综合征

    The diagnostic values of quantitative detection of cardiac troponin I in acute non Qwave myocardial infarction

    LI Bojia, WEI Jianrui, JIANG Zuofeng, CUI Jin，ZHAO Jin, LI Guobiao

    (1.Dept. of Clinical Medicine,Guangdong College of Pharmacy, Guangzhou 510224; 2. Dept. of Cardiac Internal Medicine,The Red Cross Hospital of Guangzhou，Guangzhou 510240)

    Abstract Objective: To investigate diagnostic values of cardiac troponin I (cTnI) in acute non Qwave myocardial infarction (NQAMI). Methods: Corpuscule immunochemistry photogenic method was applied to quantitatively detect serum cTnI concentration of 23 cases of NQAMI. The positive rate and serum CKMB were compared. Results: cTnI level increased in 23 patients. The positive rate was 100%. The peak average value was 20 times of the definition for diagnosing acute myocardial infarction. CKMB level increased in 16 patients. The positive rate was 69.9%. The peak average value was 5.6 times of the upper normal limit. Conclusions: The diagnostic sensitivity of troponin I in NQAMI is obviously higher than that of CKMB. ......

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