果糖__(期刊论文)

果糖1，6二磷酸二镁的结晶与结构分析

http://www.100md.com 《广东药学院学报》 2003年第1期

果糖,,果糖1，6二磷酸二镁；酒精-乙酸镁体系；结晶；结构分析,1材料与方法,2结果与讨论,3结论

     摘要目的：优化果糖1，6二磷酸二镁的结晶工艺，并对产物结构进行分析。方法：采用醇析和盐析相结合的结晶体系即酒精-乙酸镁体系使果糖1，6二磷酸二镁结晶，通过元素分析、红外光谱、核磁共振氢谱、13C谱及E.COSY型13C-1H相关谱等对产品结构进行分析。结果：最佳结晶工艺条件为：20 ℃、pH6.0、φ(乙醇)=70%；确定了产品的结构；结晶收率和产品的纯度分别为900%及98.5%以上。结论：该结晶方法简单可行。

    关键词果糖1，6二磷酸二镁；酒精-乙酸镁体系；结晶；结构分析

    Crystallization and characterization of dimagnesium fructose-1，6-diphosphate

    GAO Qin,WENG Wen,LUO Huanmin,ZHANG Peifen

    (College of Pharmacy，Jinan University，Guangzhou 510632)

    Abstract Objective：To optimize the crystallization technique of dimagnesium fructose-1，6-diphosphate(FDP-Mg.)and to analyze its structure. Methods： FDP-Mg was crystallized with ethanol precipitation combined with salt precipitation,i.e. ethanol-magnesium acetate. The product was characterized by means of elemental analysis,IR,1H-NMR,13C-NMR and E.COSY-type13C-1H correlation spectrum . Results：The optimal crystallizing condition was 20 ℃,pH6.0,with ethanol concentration of 70%,the structure of the product was confirmed and the yield and purity of the product were more than 90.0% and 98.5%,respectively. Conclusion：The crystallizing method is simple and feasible. ......

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