【摘 要】 目的 探讨血浆内皮素(ET)与降钙素基因相关肽(CGRP)在肺癌患者治疗前后含量的变化。 方法 应用放射免疫分析法测定38例肺癌患者和30例正常人血浆中ET、CGRP含量。 结果 肺癌患者血浆中ET水平显著高于正常人组(P<0.01)，而CGRP水平则明显低于正常人组(P<0.01)。经化疗后1个月，血浆ET仍高于正常人组(P<0.05)，CGRP水平仍低于正常人组(P<0.05)。 结论 检测肺癌患者血浆中ET和CGRP含量的变化可能与肺癌患者发生与发展有关。

    【关键词】 肺癌;内皮素;降钙素基因相关肽

    Clinical significance of plasma endothelin and calcitonim gene related peptide levels in patients with lung carcinoma SU Yan-lun.(Lianyungang Xinpu District People's Hospital，Jiangsu222002，China)

    【Abstract】 Objective To explore the changes of plasma endothelin(ET)and calcitonim gene related peptide(CGRP)levels be-fore and after treatment in patients with lung carcinoma.Methods Levels of plasma ET and CGRP were determined by RTA in38cases of lung carcinoma and30normal controls before and after treatment.Results In patients with lung carcinoma the plas-ma ET level was higher than those in normal controls(P<0.01) ......