Diagnosis, treatment and prognosis of cystic renal cell carcinoma (report of 31 cases)

    Zhang Yinan, Xia Shujie, Han Bangmin, Sun Xiaowen, Liu Haitao, Jing Yifeng

    (Department of Urology, Shanghai First People¬ðs Hospital, Shanghai 200080, China)

    ABSTRACT: Objective To assess the diagnosis, treatment and prognosis of cystic renal cell carcinoma (CRCC). Methods The epidemic, pathologic, clinical and radiological features of 31 cases of CRCC were retrospectively analyzed. CRCC was categorized using World Health Organization Classification of Tumours(2002). The prognosis was compared with nonª²cystic renal cell carcinoma of 21 cases with the same TNM classification. Results The clinical features of CRCC were similar to those of nonª²CRCCs. Histopathologic examination demonstrated 19 cases of renal cell carcinoma cystic degeneration, 9 multilocular cystic renal cell carcinoma and 3 preexisting simple cyst cancerization. 21 cases were followed. The mean followª²up period was 38 months (ranging from 4 to 118). The prognosis of cystic renal cell carcinoma is no better than that of the nonª²CRCCs. Conclusion Composed of 3 histopathologic types, cystic renal cell carcinoma refers to any type of renal carcinomas with cystic features, which may be observed by the radiological exams or during the operation. Proper diagnosis of the subtype is the key to choosing the surgical treatment and to assessing the prognosis. ......