摘要: 目的: 观察榛花的降血糖作用并初步阐明其作用机理。 方法: 采用四氧嘧啶所制实验性糖尿病小鼠模型，以对照方法测定血糖、血清超氧化物歧化酶(SOD)活性、丙二醛(MDA)含量并观察肝糖原和胰岛B细胞。 结果: 榛花可降低实验性糖尿病小鼠的血糖水平，可提高血清SOD活性并降低血清MDA含量，可提高肝糖原含量，而未能使胰岛B细胞修复和再生。 结论: 榛花具有降低实验性糖尿病小鼠高血糖的作用，而这种作用可能是通过促进肝组织糖原合成等类胰岛素样作用和清除自由基及抗脂质过氧化过程实现的。

    关键词: 榛花; 降血糖; SOD; MDA; 组织化学; 免疫组织化学

    The effects and mechanisms of hazel's flower on decreasing blood sugar

    CAI Y ing-lan， JIN X iang-zi， LI SH an-hua， PIAO L i-hua， LI J ia

    Department of histology and Embryology，Medical College of Yanbian University(Yanji133000，jilin，China)

    Abstract: Objective:to observe the effects of hazel's flower on decreasing blood sugar and clarify its mechanisms.Methods:by the mouse of experimental diabetes induced by alloxan，by the methods of control，it was measured the blood sugar，activity of superoxide dismutase(SOD)of serum，amount of malondialdehyde(MDA)of serum and observed hepatic glycogen and pancreas islet B cell.Results:The hazel's flower decreased the lever of the blood sugar and the amount of MDA，and increased the activity of SOD and the contents of hepatic glycogen，but could not make the pancreas islet B cell repaired and regenerated.Conclusion:The Hazel's flower had the effect of decreasig blood sugar on diabetic mouse induced by alloxan May be its mechanism of decreasing blood sugar was the insulin kind function of promoting synthesis of hepatic glycogen etc ......