关键词: 瘢痕;血管形成;免疫组织化学

    中图号:R619.6

    摘 要:目的 研究血管形成在增生性瘢痕形成过程中的作用. 方法 通过免疫组织化学方法采用CD34 抗体对增生性瘢痕组织的微血管进行染色. 结果 增生期的增生性瘢痕组织中微血管的含量明显高于萎缩期的增生性瘢痕及正常手术后瘢痕. 结论 瘢痕的增生可能具有一定的血管依赖性.

    Angiogenesis in hypertrophic scars:A pathology study

    WANG Zhen，GUO Shu-Zhong，ZHANG Lin-Xi，LU Kai-Hua

    Plastic Surgery Centre，Xijing Hospital，Fourth Military Medical University，Xi'an710033，China

    Keywords:cicatrix;angiogenesis;immunohistochemistry

    Abstract:AIM To investigate the role of angiogenesis in the formation of hypertrophic scars.METHODS By im-munohistochemistry，the micrangia in the hypertrophic scars were investigated.RESULTS In the proliferation stage，the microvascular density of hypertrophic scars was much higher than the mature hypertrophic scars and normal scars.CONCLUSION The formation and proliferation of hyper-trophic scars may be related to their increased level of vascu-larization.

    引言

    增生性瘢痕是整形外科最常遇到的疾病之一 ......