摘要：目的：了解多发性硬化(Multiple Sclerosis，MS)临床和常规性磁共振(MRI)以及磁共振弥散成像(DWI)的相关性。方法：分析40例确诊MS的临床表现、临床定位及核磁共振检查结果。结果：根据40例MS临床表现，病灶定位有73个，其中大脑29个，小脑5个，脑干11个，视神经16个，脊髓12个。40例MS常规MRI扫描在T2WI像上呈规则或不规则高信号占40/40，T1WI表现为低信号者占13/40，10例同时行DWI均可见明显的轻度高信号。MR发现的病灶总数为156个，其中分布在大脑半球双侧白质区94个，底节区17个，丘脑5个，脑干14个，小脑16个，脊髓10个。结论：MRI，特别是DWI有助于早期发现MS临床病灶。

    关键词：多发性硬化；常规磁共振影像；弥散磁共振影像

    Contrast the Clinical Orientations in Patients with Multiple Sclerosis with the Characteristics of Magnetic Resonance Imaging (MRI) and Diffusion Weighted Imaging (DWI)

    LIU Lian,et al

    (The Second Affiliated Hospital，Shantou University Medical College, Guangdong Shantou 515041，China)

    Abstract: Objective: To investigate the pertinency between the clinical characteristics in patients with Multiple Sclerosis and their characteristics of magnetic resonance imaging (MRI) or diffusion weighted imaging (DWI). Method: To analyse the clinical features, clinical orientations and their characteristics of magnetic resonance imaging (MRI) or diffusion weighted imaging (DWI) in 40 cases with Multiple Sclerosis.Result: According to the clinical features, there were 73 clinical orientations in all, of them 29 orientations in cerebrum, 5 orientations in cerebellum, 11 orientations in brainstem, 16 orientations in optic nerve and 12 orientations in spinal cord. 40 cases where checked-up by MRI, 10 of them checked-up by DWI. 156 lesions were demonstrated by MRI and DWI, of them 94 were found in white matter, 17 lesions in basal gangli area, 5 lesions in thalamus, 14 lesions in brainstem, 16 lesions in cerebellum and 10 lesions in spinal cord. Conclusion: MRI, especially the DWI, may help to find those lesions without clinical features of Multiple Sclerosis early. ......