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丹参对大鼠缺血后残肝有效血流量的影响
http://www.100md.com 《中华实验外科杂志》 1999年第6期
SPECT|缺血|有效血流量|丹参,关键词:
     张志伟 吴在德 陈孝平 赵明 吴华 张志伟 吴在德 陈孝平 430030 武汉,同济医科大学同济医院普通外科,赵明 吴华 核医学科 中华实验外科杂志 1999 0 16 6


    关键词:SPECT;缺血;有效血流量;丹参 期刊 zhsywkzz 0 论 著 fur -->


    

【摘要】 目的 探讨丹参对大鼠缺血后残肝有效血流量的影响。方法 应用SPECT测定鼠残肝有效血流量变化。结果 肝部分切除术后残肝有效血流量下降(P<0.001);缺血组残肝有效血流量明显低于对照组(P<0.001),术后第7天仍低于术前水平(P<0.05);丹参组残肝有效血流量明显高于缺血组(P<0.001),术后第7天达正常水平。结论 缺血残肝有效血流量下降,丹参能增加缺血残肝有效血流量,对残肝再生产生有益的影响。

Dynamic observation on the influence of Labiatae on effective blood flow of ischemic liver remnant in rats

ZHANG Zhiwei, WU Zaide, CHEN Xiaoping, et al.

    Department of General Surgery, Tongji Hospital, Tongji Medical University, Wuhan 430030

【Abstract】 Objective To investigate the influence of Labiatae on effective blood flow (EBF) of ischemic liver remnant (ILR). Methods The changes in EBF of ILR were determined by using single-phoron emission computed tomography (SPECT). Results The EBF of liver remnant was decreased after partial hepatectomy (P<0.001). The postoperative EBF of ILR was less than that in control group (P<0.001). On the 7th postoperative day, the EBF of ILR was still decreased as compared with preoperative. The EBF of ILR in Labiatae group was higher than that in ischemic group. On 7th postoperative day, the EBF of Labiatae group returned to the normal level. Conclusion The EBF of liver remnant was decreased after partial hepatectomy, especially with ILR. Labiatae can increase the EBF of ILR and take a beneficial effect to the liver regeneration.

    【Key words】 SPECT Ischemia EBF Labiatae

肝再生是一种复杂的生物学行为 ......


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