关键词:上颌窦肿瘤;放射治疗;药物疗法;手术治疗
摘 要 :目的 :探讨化疗、放疗与手术联合治疗晚期上颌窦癌的可行性。方法 :术前放疗和手术61例,术前化疗和手术60例。放疗采用直线加速器和(或)60 Co,剂量为40~60Gy。化疗采用DOP(顺氯氨铂加长春新碱加平阳霉素)方案。结果 :放疗和手术组3年和5年生存率分别为36.1%和31.1%;化疗和手术组分别为35%和30%。结论 :术前化疗加手术是治疗晚期上颌窦癌的可行性方法,且化疗能反复应用,提高手术效果。
Combined therapy for 121 cases of advanced cancer of th e maxillary sinus
LI Tian-xin WEI Lin JING Guo-ping YU Shu-guan
(Henan Tumour Hospital,Zhengzhou 450003)
Abstract :Objective :To investigate the posibllity of combined therapy (chemotherapy+surgery)for advanced cancer of maxillary sin us.Method :Pre-operative radiation+surgery for 61 cases an d preoperative chemotherapy+operation for 60 cases were performed.Radiotherapy referred to the use of linear accelerator and/or 60 Co with the dosage of 40~60 Gy.Chemotherapy referred to the administration of CDDP.VCR,and pingyangmycin.Result :The survival rate observed in the 61 cases treated wit h radiation+operation was 36.1%;while the other 60 cases treated by chenothe rapy+operation had a survival rate of 31.1%.Conclusion :The better way to treat advanced cancer of the maxillary simus is pre-operati ve chematherapy+surgery.In addition,repeated application of chemotherapy can rai se the effect of surgical treatment.
Key words :Maxillary sinus neoplasms Radiotherapy Drug t herapy Surgical treatment
晚期上颌窦癌最易侵犯周围组织和器官 ......
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