【摘要】 目的 研究阻塞性睡眠呼吸暂停综合征(OSAS)对老年高血压患者血压及其昼夜节律的影响。方法 84例研究对象分为OSAS组、高血压(HT)组和OSAS+HT组。观察呼吸暂停低通气指数(AHI)、皮质微觉醒指数(CAI)、运动微觉醒指数(MAI)及氧饱和度低于90%的时间(OLT90%)对24h血压及血压昼夜节律的影响。结果 影响OSAS+HT组的24h平均收缩压(ASBP)和平均舒张压(ADBP)的主要因素是MAI，次要因素是OLT90%;OSAS+HT组昼夜血压曲线呈非勺形的发生率高于单纯HT组。结论 OSA与HT及其昼夜血压变化独立相关;非勺型血压曲线的增加可能是OSAS患者心血管事件增加的重要危险因素。

    关键词 睡眠呼吸暂停综合征 高血压 昼夜节律 觉醒 低氧

    Correlation of obstructive sleep apnea with blood pressure and its circadian rhythm in hypertensive patients of the aged

    He Qing，Lin Yun，Liang Wei，et al.

    High Cadre Ward，The Affiliated Ruijin Hospital of Second Medical University，Shanghai200025.

    【Abstract】 Objective To demonstrate the influence of obstructive sleep apnea syndrome on blood pressure and its circadian rhythm in essential hypertensive patients of the aged.Methods Eighty-four subjects were divided into OSAS group ......