经皮二尖瓣球囊成形术远期疗效评价(摘要)
作者：鞠桂芬
单位：辽宁省大连市，大连友谊医院(116001)
关键词：
中国循环杂志99zk106 目的：评价经皮二尖瓣球囊成形术(PBMV)后10年以上的远期疗效。
方法：我院从1988年1月～1989年11月成功的进行PBMV 11例，术后至今进行了严格的追踪随访10年，用随诊超声心动图和临床心功能评价。平均随诊时间10.8±1.3年。
结果：PBMV术后即刻二尖瓣口面积(MVA)显著扩大(由1.08±0.33 cm2到2.03±0.42 cm2),P<0.01；随访10年，MVA逐渐减小至1.46±0.35 cm2,P<0.01；再狭窄率为39.3%。PBMV术后心功能改善Ⅰ级以上者占96.4%。术后10年随访心功能仍然保持在Ⅰ～Ⅱ级而未再次行介入治疗或心脏手术者占78.3%。术后新出现或轻度加重的二尖瓣反流分别为12.8%和8.1%,均未引起明显的血液动力学障碍，长期保持良好的心功能。
结论：PBMV术后10年以上临床远期疗效良好，未见严重并发症。
Evaluation on Long-Term Results of Percutaneous Balloon Mitral Valvuloplasty (Abstract)
Dalian Friendship Hospital, Dalian (116001), Liaoning
Ju Guifen
Objective: This study was sought to assess long-term results (more than ten years) after successful percutaneous balloon mitral valvuloplasty.
Methods: From January 1988 to Novermber 1989, 11 patients underwent PBMV successfully in Dalian Friendship Hospital of which seventy nine patients had clinical and echocardiographic evaluation initially and throughout the 10-year follow-up.
Results: Before and after PBMV and at follow-up, mean mitral valve areas were 1.08±0.33 cm vs. 2.03±0.42 cm vs. 1.46±0.35 cm respectively (before vs. after p<0.01, after vs. follow-up p<0.01, before vs. follow-up p<0.01). Restenosis rate was 39.3% at the end of 10-year follow-up. There were seventy-seven (96.4%) patients who had at least Ⅰ class improvement in cardiac function just after PBMV. At the end of 10-year follow-up, 78.3% patients were still in NYHA class Ⅰ or Ⅱ without mitral operation or repeated valvuloplasty. There were 12.8% and 8.1% of patients had new mitral regurgitations and atrial septal defects respectively, but none experienced serious dynamic impairment.
Conclusion: Percutaneous balloon mitral valvuloplasty can achieve excellent and sustained long-term results without serious complications in selected patients., 百拇医药
单位：辽宁省大连市，大连友谊医院(116001)
关键词：
中国循环杂志99zk106 目的：评价经皮二尖瓣球囊成形术(PBMV)后10年以上的远期疗效。
方法：我院从1988年1月～1989年11月成功的进行PBMV 11例，术后至今进行了严格的追踪随访10年，用随诊超声心动图和临床心功能评价。平均随诊时间10.8±1.3年。
结果：PBMV术后即刻二尖瓣口面积(MVA)显著扩大(由1.08±0.33 cm2到2.03±0.42 cm2),P<0.01；随访10年，MVA逐渐减小至1.46±0.35 cm2,P<0.01；再狭窄率为39.3%。PBMV术后心功能改善Ⅰ级以上者占96.4%。术后10年随访心功能仍然保持在Ⅰ～Ⅱ级而未再次行介入治疗或心脏手术者占78.3%。术后新出现或轻度加重的二尖瓣反流分别为12.8%和8.1%,均未引起明显的血液动力学障碍，长期保持良好的心功能。
结论：PBMV术后10年以上临床远期疗效良好，未见严重并发症。
Evaluation on Long-Term Results of Percutaneous Balloon Mitral Valvuloplasty (Abstract)
Dalian Friendship Hospital, Dalian (116001), Liaoning
Ju Guifen
Objective: This study was sought to assess long-term results (more than ten years) after successful percutaneous balloon mitral valvuloplasty.
Methods: From January 1988 to Novermber 1989, 11 patients underwent PBMV successfully in Dalian Friendship Hospital of which seventy nine patients had clinical and echocardiographic evaluation initially and throughout the 10-year follow-up.
Results: Before and after PBMV and at follow-up, mean mitral valve areas were 1.08±0.33 cm vs. 2.03±0.42 cm vs. 1.46±0.35 cm respectively (before vs. after p<0.01, after vs. follow-up p<0.01, before vs. follow-up p<0.01). Restenosis rate was 39.3% at the end of 10-year follow-up. There were seventy-seven (96.4%) patients who had at least Ⅰ class improvement in cardiac function just after PBMV. At the end of 10-year follow-up, 78.3% patients were still in NYHA class Ⅰ or Ⅱ without mitral operation or repeated valvuloplasty. There were 12.8% and 8.1% of patients had new mitral regurgitations and atrial septal defects respectively, but none experienced serious dynamic impairment.
Conclusion: Percutaneous balloon mitral valvuloplasty can achieve excellent and sustained long-term results without serious complications in selected patients., 百拇医药