心脏MRI的介绍.ppt
http://www.100md.com
参见附件(3093kb)。
簡介
Important views
做心臟MRI的技巧
* Spatial resolution & temporal resolution
* ECG gating
* 其他
Cardiac MRI 的分類
* Global function
* Local wall motion
* Myocardium viability
* Perfusion (microcirculation)
* DTI: Diffusion Tensor Imaging
Global function
* 大部分都是在做Left ventricle 的分析. 用Cine 配合心臟不同的phase加上不同的平面來測量出 *EF, PFR, PER, ESV, (n)EDV, (n)ESV etc.
* EF= Ejection fraction, PFR= peak filling rate, PER= peak ejecting rate,EDV= end diastolic volume , ESV= end systolic volume
另一種方法
* 取 4-chamber view
Local wall motion
* 心臟有三條主要供應血管:
1. Left anterior descending (LAD),2. Right coronary artery (RCA),3. Left circumflex coronary artery (LCX)
Apical 4-chamber
Myocardium Viability
* 主要是利用delay contrast enhancement的原理
* 用的 contrast agent 是 Gadolinium-diethyleneaminepentaacetate (Gd-DTPA)
* 分辨 normal / infarcted or scarred myocardium
Perfusion
* MR perfusion 的原理和核子醫學部的Thalium-201 stress/rest perfusion 一樣
* 目前還屬於研究階段
LV perfusion
DTI - myocardial fiber
結論
* Cardiac MRI 是個非侵入性的檢查, 而且由它所提供的數據在心臟生理與病理功能上有相當珍貴的價值, 更何況現在的數據都已經走向量化, 所以可以更精準的做出診斷. MRI配上MRS再加上在機器或pulse sequence上的進步, 相信在不久的未來真的能夠達到 --- "把人做分子化的檢查"
References
* John R. Forder and Gerald M. Pohost
Cardiovascular nuclear magnetic resonance: basic and clinical applications
Copyright (c) 2003, American Society for Clinical Investigation J Clin Invest. 2003 June 1; 111 (11): 1630-1639
* James M. Wilson, MD, Rollo P. Villareal, MD, Ramesh Hariharan, MD, Ali Massumi, MD, Raja Muthupillai, PhD, and Scott D. Flamm, MD
Magnetic Resonance Imaging of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
Copyright (c) 2002, Texas Heart(r) Institute, Houston Tex Heart Inst J. 2002; 29 (3): 176-180
* http://circ.ahajournals.org/cgi/content/full/105/4/539
Special thanks
* Marine SU
Thanks for your attention !
簡介
Important views
做心臟MRI的技巧
* Spatial resolution & temporal resolution
* ECG gating
* 其他
Cardiac MRI 的分類
* Global function
* Local wall motion
* Myocardium viability
* Perfusion (microcirculation)
* DTI: Diffusion Tensor Imaging
Global function
* 大部分都是在做Left ventricle 的分析. 用Cine 配合心臟不同的phase加上不同的平面來測量出 *EF, PFR, PER, ESV, (n)EDV, (n)ESV etc.
* EF= Ejection fraction, PFR= peak filling rate, PER= peak ejecting rate,EDV= end diastolic volume , ESV= end systolic volume
另一種方法
* 取 4-chamber view
Local wall motion
* 心臟有三條主要供應血管:
1. Left anterior descending (LAD),2. Right coronary artery (RCA),3. Left circumflex coronary artery (LCX)
Apical 4-chamber
Myocardium Viability
* 主要是利用delay contrast enhancement的原理
* 用的 contrast agent 是 Gadolinium-diethyleneaminepentaacetate (Gd-DTPA)
* 分辨 normal / infarcted or scarred myocardium
Perfusion
* MR perfusion 的原理和核子醫學部的Thalium-201 stress/rest perfusion 一樣
* 目前還屬於研究階段
LV perfusion
DTI - myocardial fiber
結論
* Cardiac MRI 是個非侵入性的檢查, 而且由它所提供的數據在心臟生理與病理功能上有相當珍貴的價值, 更何況現在的數據都已經走向量化, 所以可以更精準的做出診斷. MRI配上MRS再加上在機器或pulse sequence上的進步, 相信在不久的未來真的能夠達到 --- "把人做分子化的檢查"
References
* John R. Forder and Gerald M. Pohost
Cardiovascular nuclear magnetic resonance: basic and clinical applications
Copyright (c) 2003, American Society for Clinical Investigation J Clin Invest. 2003 June 1; 111 (11): 1630-1639
* James M. Wilson, MD, Rollo P. Villareal, MD, Ramesh Hariharan, MD, Ali Massumi, MD, Raja Muthupillai, PhD, and Scott D. Flamm, MD
Magnetic Resonance Imaging of Myocardial Fibrosis in Hypertrophic Cardiomyopathy
Copyright (c) 2002, Texas Heart(r) Institute, Houston Tex Heart Inst J. 2002; 29 (3): 176-180
* http://circ.ahajournals.org/cgi/content/full/105/4/539
Special thanks
* Marine SU
Thanks for your attention !
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